cMyBP-C Phosphorylation at S273 and S282 Decrease Linearly With Age
Pearson correlation analyses and linear regressions were performed on cMyBP-C site-specific phosphorylation Western blots for cMyBP-C(tWT) with n = 16 at ages 2 to 24 months. Correlation coefficient (–1 to 1) quantifies strength of correlation, in which strong is: |coefficient| > 0.5; moderate is: 0.3 ≤ |coefficient| < 0.5; and weak is: 0.1 ≤ |coefficient| < 0.3. (A) Analyses showed that cMyBP-C S273 phosphorylation decreased in a strongly correlated linear fashion with increasing age. (B) Analyses showed that cMyBP-C S282 phosphorylation decreased in a strongly correlated linear fashion with increasing age. (C) cMyBP-C S302 phosphorylation did not correlate with increasing age.